Pharmaceutical Treatment Options For The Treatment Of Type...

A myriad of pharmaceutical treatment options for the treatment of type 2 diabetes (T2DM) currently exist (Inzucchi et al., 2015; American Diabetes Association, 2016). Although metformin remains the first-line pharmacologic treatment, numerous options are available when metformin alone does not achieve glycemic targets. When making treatment decisions, the American Diabetes Association (ADA, 2016) recommends that selection of additional agents should take into account the advantages and disadvantages of specific medications. They also advise consideration of patient preference, cost, side effects, impact on body weight, and risk for hypoglycemia (ADA, 2016). The intent of this paper is to explore the recently published and highly relevant research findings on the impact of empagliflozin, a sodium glucose co-transporter-2 inhibitor (SGLT2), on cardiovascular outcomes and mortality (Zinman et al., 2015). Empagliflozin (EMPA), along with other SGLT2 drugs, effectively work to reduce glycemia by suppressing renal glucose reabsorption (Rosenstock, et al., 2015). The end result is reduced blood glucose, because of increased urinary glucose excretion. Rosenstock and colleagues (2015) conducted a randomized, control trial comparing the impact of long acting insulin versus long acting insulin plus EMPA. The 79-week trial was conducted from 2009 to 2012 and included 97 centers in seven countries, including the United States. In total, 494 participants were included. AfterShow MoreRelatedDrug Product Review Of Canagliflozin1116 Words   |  5 Pagesimprovement of glycemic control for adults with type 2 diabetes. In 2013, Elkinson and Scott estimated that there were approximately 220 million people worldwide affected by type 2 diabetes. Despite having multiply classifications of drugs and typically multiple drugs to each classification, more than have of patient being treated do not ha ve adequate control of their diabetes (Elkinson Scott, 2013). As mentioned before with so many medication types already on the market, is Canagliflozin a beneficialRead MoreAlternative Weight Loss In Obesity Essay904 Words   |  4 Pagescompared in terms of how they work, their side effects, and the duration of their effectiveness so obese adults can pick an option that is compatible for their condition(s) and personal preferences. This paper will answer the question stated above by evaluating the two options using evidence. Background Obesity is easily noticeable and diagnosable. The easiest diagnostic option is calculating a patients body mass index or BMI. Being obese is classified as having a BMI that is 30 and over (Mayo ClinicRead MoreWhat Is Canagliflozin At Lowering Blood Glucose Levels?947 Words   |  4 Pagesinformation: Answer: †¢ The literature used to research this topic suggest that canagliflozin is a better option than empagliflozin at lowering blood glucose (A1C) levels in diabetic patients. According to the package inserts for both drugs, genital mycotic infections and urinary tract infections are likely to occur, especially in women, because of the mechanism of the drugs. 1,2 Background: Type 2 diabetes is a chronic disorder in which the body does not properly respond to insulin well, thus allowing highRead MoreBenefits Of Financial Support For Medical And Health Care1182 Words   |  5 PagesAccordingly, medical products were controlled by technological standards. Many countries use economic valuation if their medical and health systems should finance certain pharmaceutical and pharmaceutical preparations. 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